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Dissecting therapeutic resistance to RAF inhibition in melanoma by tumor genomic profiling

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Recently, a class of ferroptosis inhibitors that target NCOA4 has been identified

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In May 2026, Lilly announced that the phase III TRIUMPH-1 study, which evaluated the efficacy and safety of three doses (4 mg, 9 mg and 12 mg) of retatrutide for 80 weeks against placebo in adults with obesity or overweight, met its primary endpoint